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Apolipoprotein E (apoE) polymorphism is an important genetic risk factor for ischemic cerebrovascular disease, including stroke. However, the association between apoE polymorphism and stroke is still controversial. To examine the significance of apoE polymorphism in predicting acute cerebral infarction, we have analyzed the apoE genotypes in 97 Japanese patients with acute cerebral infarction (45 cases of lacunar infarction and 52 cases of atherosclerotic infarction) and in 152 Japanese control subjects. The apoE genotypes were determined by the method of polymerase chain reaction and electrophoresis on agarose gel. Of all the patients with acute cerebral infarction, 33.3% (33 of 97) were apoE epsilon4 carriers. The frequency of epsilon4 allele was significantly higher in the group of patients with lacunar infarction than in the control subjects (9.1% vs 0.6%, P =.0003). Our results suggest that the epsilon4 allele is a genetic risk factor in lacunar infarction in Japanese.Boat Hire in Beadnell Bay
Looking for a boat hire company in Beadnell Bay then you have come to the right place. We are a family run company and have been providing Beadnell Bay with boat rentals for over 30 years and can provide you with some great tips for day trips whilst you are there.
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One of our most popular trips is to Beadnell Lakes, a beautiful day trip with the option of lunch onboard and the chance to try some fishing. If you want to upgrade to the Captain’s Lunch you can do that too! Here are some great places to eat on Beadnell Lakes:
There are also some great scenery and there is even a perfect spot for a picnic to take place on the lake.
Check our website for boat hire prices and availability.
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